Osteoporosis is one of the common diseases among the elderly in clinical practice, and it is more common in postmenopausal women; With the extension of postmenopausal time, the incidence rate of osteoporosis in middle-aged and elderly women can increase significantly, indicating that estrogen secreted by the ovary has an important impact on the occurrence and development of osteoporosis. The osteoporosis model replicated by ovariectomy in rats is currently the best model recommended by WHO and the US FDA for studying postmenopausal osteoporosis.

Observation indicators

Bone density testing and pathological analysis; Electron microscopy scanning showed that the thickness of the distal femur on the left side of the model group was uneven, and the gap increased; The arrangement of bone trabeculae is disordered, and the number of bone pits is significantly increased compared to the model group.

Partial Results Display